Back to search

Article

Cry1Ac toxin and protoxin affect intestinal barrier function by altering zonula occludens-1 and activating mitogen-activated protein kinase pathways in a Caco-2 cell monolayer model of the human intestinal mucosa

2023-08-22

Abstract excerpt

The Cry proteins produced by Bacillus thuringiensis are widely used as bioinsecticides to control crop plagues; they have been considered innocuous for vertebrates. Currently, distinct truncated forms of the genes encoding Cry toxins are expressed in genetically transformed crops that are used for animal and human consumption. Cry1Ac is one of these proteins to which humans are exposed. Our group has demonstrated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9289b4e8-f1d2-57c8-a644-ef9e8470408b
DOI
10.21203/rs.3.rs-3256816/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Cry1Ac toxin and protoxin affect intestinal barrier function by altering zonula occludens-1 and activating mitogen-activated protein kinase pathways in a Caco-2 cell monolayer model of the human intestinal mucosaDOI 10.21203/rs.3.rs-3256816/v1
Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology.Semantic proximity
Immunotoxicological evaluation of corn genetically modified with Bacillus thuringiensis Cry1Ah gene by a 30-day feeding study in BALB/c mice.Semantic proximity
Pesticidal and receptor binding properties of Bacillus thuringiensis Cry1Ab and Cry1Ac delta-endotoxin mutants to Pectinophora gossypiella and Helicoverpa zea.Semantic proximity
Bacillus thuringiensis bel protein enhances the toxicity of Cry1Ac protein to Helicoverpa armigera larvae by degrading insect intestinal mucin.Semantic proximity
The Food Poisoning Toxins of Bacillus cereusSemantic proximity
Enterotoxigenic Bacteroides fragilis : a Rogue among SymbiotesSemantic proximity
Induction of Persistent Colitis by a Human Commensal, Enterotoxigenic<i>Bacteroides fragilis</i>, in Wild-Type C57BL/6 MiceSemantic proximity
Bacterial protein toxins in human cancersSemantic proximity
Pathophysiological mechanisms of diarrhea caused by the Vibrio cholerae O1 El Tor variant: an in vivo study in mice.Semantic proximity
The Caenorhabditis elegans CUB-like-domain containing protein RBT-1 functions as a receptor for Bacillus thuringiensis Cry6Aa toxin.Semantic proximity
Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects.Semantic proximity
Regulation of Intercellular Tight Junctions by Zonula Occludens Toxin and Its Eukaryotic Analogue ZonulinSemantic proximity
Select a neighboring publication to make it the new centre.