Article
The Caenorhabditis elegans CUB-like-domain containing protein RBT-1 functions as a receptor for Bacillus thuringiensis Cry6Aa toxin.
PLoS pathogens - 1 May 2020
Shi Jianwei, Peng Donghai, Zhang Fengjuan, Ruan Lifang, Sun Ming
Abstract excerpt
Plant-parasitic nematodes cause huge agricultural economic losses. Two major families of Bacillus thuringiensis crystal proteins, Cry5 and Cry6, show nematicidal activity. Previous work showed that binding to midgut receptors is a limiting step in Cry toxin mode of action. In the case of Cry5Ba, certain Caenorhabditis elegans glycolipids were identified as receptors of this toxin. However, the receptors for Cry6...
Topics
- Animals
- Bacillus thuringiensis
- Bacillus thuringiensis Toxins
- Bacterial Proteins
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Endotoxins
- Hemolysin Proteins
- Membrane Microdomains
- Mutation
- Oligosaccharides
- Receptors, Cell Surface