Back to search

Article

Human papillomavirus 16 positive cervical cancer in Guatemala: The D2 and D3 sublineages differ in integration rate and age of diagnosis

2020-01-08

Abstract excerpt

Human papillomavirus (HPV) 16 displays substantial sequence variation; four HPV16 lineages (A, B, C, D) have been described, as well as multiple sub-lineages. To identify molecular events associated with HPV16 carcinogenesis we evaluated viral variation, the integration of HPV16, and somatic mutation in 96 cervical cancer samples from Guatemala. A total of 64% (60/94) of the samples had integrated HPV16 sequences,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9267b1d1-9b31-5229-a22a-66771c82ba12
DOI
10.1101/2020.01.07.897546
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Human papillomavirus 16 positive cervical cancer in Guatemala: The D2 and D3 sublineages differ in integration rate and age of diagnosisDOI 10.1101/2020.01.07.897546
The D2 and D3 Sublineages of Human Papilloma Virus 16-Positive Cervical Cancer in Guatemala Differ in Integration Rate and Age of Diagnosis.Semantic proximity
HPV16 Phylogenetic Variants in Anogenital and Head and Neck Cancers: State of the Art and Perspectives.Semantic proximity
Cervical Cancer Stages, Human Papillomavirus Integration, and Malignant Genetic Mutations: Integrative Analysis of Datasets from Four Different CohortsSemantic proximity
HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samplesSemantic proximity
HPV16 Sublineage Associations With Histology-Specific Cancer Risk Using HPV Whole-Genome Sequences in 3200 WomenSemantic proximity
HPV16 and HPV18 type-specific APOBEC3 and integration profiles in different diagnostic categories of cervical samplesSemantic proximity
Epidemiology and Molecular Biology of HPV Variants in Cervical Cancer: The State of the Art in MexicoSemantic proximity
Differential HPV16 variant distribution in squamous cell carcinoma, adenocarcinoma and adenosquamous cell carcinoma.Semantic proximity
Human Papillomavirus 16 Non-European Variants Are Preferentially Associated with High-Grade Cervical LesionsSemantic proximity
Human papillomavirus type 16 sub-lineages and integration in cancerSemantic proximity
Human papillomavirus 16 sub-lineage dispersal and cervical cancer risk worldwide: Whole viral genome sequences from 7116 HPV16-positive womenSemantic proximity
Human Papillomavirus 16 lineage D is associated with high risk of cervical cancer in the Brazilian Northeast regionSemantic proximity
Select a neighboring publication to make it the new centre.