Article

Improving T-cell mediated immunogenic epitope identification via machine learning: the neoIM model

2022-06-04

Abstract excerpt

The identification of immunogenic peptides that will elicit a CD8+ T cell-specific immune response is a critical step for various immunotherapeutic strategies such as cancer vaccines. Significant research effort has been directed towards predicting whether a peptide is presented on class I major histocompatibility complex (MHC I) molecules. However, only a small fraction of the peptides predicted to bind to MHC I...

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Literature Corpus work: 9204f383-95e4-5151-8cb2-76c318ecb285
DOI: 10.1101/2022.06.03.494687

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