Article

Automated segmentation by deep learning of neuritic plaques and neurofibrillary tangles in brain sections of Alzheimer’s Disease Patients

2023-11-02

Abstract excerpt

Alzheimer’s Disease (AD) is a neurodegenerative disorder with complex neuropathological features, such as phosphorylated tau (p-tau) positive neurofibrillary tangles (NFTs) and neuritic plaques (NPs). The quantitative evaluation of p-tau pathology is a key element for the diagnosis of AD and other tauopathies. Assessment of tauopathies relies on semi-quantitative analysis and does not consider lesions heterogeneit...

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Literature Corpus work: 7cef0a62-1af0-5c3c-ad51-3ee23b19cf9a
DOI: 10.1101/2023.10.31.564976

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