Article

A characterization of mitotic and centrosomal defects in a continuum model of Breast Cancer

2024-09-22

Abstract excerpt

<h4>ABSTRACT</h4> Errors in mitosis can contribute to aneuploidy and CIN and play a pivotal role in cancer. So the identification of altered mitotic regulators can contribute to the understanding of the development and progression of breast cancer. In the present study we used an in vitro model of disease progression (the MCF10A series of BC continuum) and analyzed the errors of chromosome segregation that occur...

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Literature Corpus work: 91f0c9a1-1b50-54e3-ae2a-699801b2bbcc
DOI: 10.1101/2024.09.20.614099

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