Article

Generation and Functional Characterization of PLAP CAR-T Cells against Cervical Cancer Cells

2022-06-14

Abstract excerpt

Chimeric antigen receptor (CAR) T cell therapy is one of the cancer treatment modalities that has recently shown promising results in treating hematopoietic malignancies. However, one of the obstacles that need to be addressed in solid tumors is the on-target/off-tumor cytotoxicity due to the lack of specific tumor antigens with low expression in healthy cells. Placental alkaline phosphatase (PLAP) is a shared pla...

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Literature Corpus work: 91c76d76-8510-5a64-8116-20a3744cec1b
DOI: 10.1101/2022.06.12.495798

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