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MGMT Gene Promoter Methylation by Pyrosequencing Method Correlates Volumetric Response and Neurological Status in IDH Wild-type Glioblastomas

2022-02-28

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<title>Abstract</title> <p>Purpose Although the usefulness of <italic>O⁶</italic>-methylguanine DNA methyltransferase (MGMT) promoter methylation analysis for predicting response to chemoradiotherapy and the prognosis of patients with glioblastoma has been widely reported, there is still no consensus regarding how to define MGMT promoter methylation percentage (MGMTpm%) cutoffs by pyrosequencing method. The aim...

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Literature Corpus work
91c1ead7-8979-54c7-a622-96c4d4b48f42
DOI
10.21203/rs.3.rs-1394692/v1
Open publication

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MGMT Gene Promoter Methylation by Pyrosequencing Method Correlates Volumetric Response and Neurological Status in IDH Wild-type GlioblastomasDOI 10.21203/rs.3.rs-1394692/v1
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