The TERT promoter mutation status and MGMT promoter methylation status, combined with dichotomized MRI-derived and clinical features, predict adult primary glioblastoma survival.

Abstract excerpt

PURPOSE: This study aimed to integrate the TERT promoter mutation status, MGMT promoter methylation status, MRI-derived features, and clinical features into a survival analysis model to better understand adult primary glioblastoma prognosis-related markers. METHOD: A total of 304 adult glioblastoma samples collected after surgical resection were selected for retrospective analysis, and Sanger sequencing was...

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