Article

Quantitative analysis of MGMT promoter methylation status changes by pyrosequencing in recurrent glioblastoma

2022-04-29

Abstract excerpt

<h4>Background: </h4> MGMT promoter methylation status can change in response to several factors, including treatment with alkylating agents. Some authors have attempted to quantify these alterations with inconsistent results. This study aims to determine changes in MGMT promoter methylation status by pyrosequencing, which quantitatively yields results, providing percentages of methylation of a given CpG dinucleot...

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Literature Corpus work: 7c708440-e2f3-5360-878b-a7a84565bef0
DOI: 10.21203/rs.3.rs-1542406/v1

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