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Metagenome-assembled genomes from a population-based cohort uncover novel gut species and within-species diversity, revealing prevalent disease associations

2024-07-09

Abstract excerpt

<h4>ABSTRACT</h4> Metagenomic profiling has advanced understanding of microbe-host interactions. However, widely used read-based approaches are limited by incomplete reference databases and the inability to resolve strain-level variation. Here, we present a scalable, genome-resolved framework that integrates population-specific metagenome assembled genomes (MAGs) to discover novel species, sub-species diversity,...

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Literature Corpus work: 8d07eac2-8df2-5528-bc46-ede9e125a389
DOI: 10.1101/2024.07.06.602324

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