Article

Top-DTI: Integrating Topological Deep Learning and Large Language Models for Drug Target Interaction Prediction

2025-02-08

Abstract excerpt

<h4>Motivation</h4> The accurate prediction of drug–target interactions (DTI) is a crucial step in drug discovery, providing a foundation for identifying novel therapeutics. Traditional drug development is both costly and time-consuming, often spanning over a decade. Computational approaches help narrow the pool of compound candidates, offering significant starting points for experimental validation. In this stud...

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Literature Corpus work: 9154129c-5ea8-5870-931b-d60e6878acf6
DOI: 10.1101/2025.02.07.637146

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