Article

FLONE: fully Lorentz network embedding for inferring novel drug targets

2023-03-23

Abstract excerpt

Motivation: To predict novel drug targets, graph-based machine learning methods have been widely used to capture the relationships between drug, target, and disease entities in heterogeneous biological networks. However, most of the existing methods cannot explicitly consider disease types when predicting targets. More importantly, drug-disease-target (DDT) networks could exhibit multi-relational hierarchical sub-...

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Literature Corpus work: 6ed36abb-6a80-590f-ae3c-bb7a58fc82f0
DOI: 10.1101/2023.03.20.533432

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