Article

Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast

2024-02-23

Abstract excerpt

It has been well-validated that chronic psychological stress leads to bone loss, but the underlying mechanism remains unclarified. In this study, we established and analyzed the chronic unpredictable mild stress (CUMS) mice to investigate the miRNA-related pathogenic mechanism involved in psychological stress induced osteoporosis. Our result found that these CUMS mice exhibited osteoporosis phenotype that mainly a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 910edca8-a25c-5e99-85f2-ca313ef7b52e
DOI: 10.1101/2024.02.20.581167

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclastDOI 10.1101/2024.02.20.581167Read

c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone RemodelingSemantic proximity Read

Stress and Alterations in Bones: An Interdisciplinary PerspectiveSemantic proximity Read

Psychological stress and aging: role of glucocorticoids (GCs).Semantic proximity Read

Multi-omics analysis of bone marrow mesenchymal stem cell differentiation differences in osteoporosisSemantic proximity Read

Transcriptional regulation of bone and joint remodeling by NFATSemantic proximity Read

Bone turnover markers and transcriptomes changes induced by acute sleep deprivationSemantic proximity Read

Role and Regulation of Transcription Factors in OsteoclastogenesisSemantic proximity Read

Gone with the Wnts: β-Catenin, T-Cell Factor, Forkhead Box O, and Oxidative Stress in Age-Dependent Diseases of Bone, Lipid, and Glucose MetabolismSemantic proximity Read

Bone development and inflammatory disease is regulated by AP-1 (Fos/Jun)Semantic proximity Read

Fosl1 is a transcriptional target of c-Fos during osteoclast differentiationSemantic proximity Read

Minireview: Live and Let Die: Molecular Effects of Glucocorticoids on Bone CellsSemantic proximity Read

Redundant miR-3077-5p and miR-705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrowSemantic proximity Read