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Minireview: Live and Let Die: Molecular Effects of Glucocorticoids on Bone Cells

28 May 2009

Abstract excerpt

Glucocorticoids (GCs) are efficient drugs that are used to treat various immune-mediated diseases, but their long-term administration is associated with multiple metabolic side effects, including osteoporosis. Molecular analyses of the mechanisms exerted by the GC receptor have resulted in the development of GC receptor agonists that selectively repress or activate GC target genes. This review summarizes the...

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PMID: 19477950
DOI: 10.1210/me.2009-0069

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