Article

The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs

2022-08-29

Abstract excerpt

Clear evidence shows that tumor could secrete microRNAs (miRNAs) via exosomes to modulate tumor microenvironment (TME). However, the mechanisms sorting specific miRNAs into exosomes are still unclear. In order to study the biological function and characterization of exosomal miRNAs, we performed whole-transcriptome sequencing in 59 patients’ whole course cerebrospinal fluid (CSF) small extracellular vesicles (sEV)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 91092158-6b2f-527d-97de-cf3b62fc6f51
DOI: 10.21203/rs.3.rs-688675/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCsDOI 10.21203/rs.3.rs-688675/v2Read

Targeting miR-9 in Glioma Stem Cell-Derived Extracellular Vesicles: A Novel Diagnostic and Therapeutic BiomarkerSemantic proximity Read

CSRP2 is involved in immune regulation and drug sensitivity in glioma cells by the LEF1- AS1/miR-128-3p/CSRP2 axisSemantic proximity Read

DNA Associated with Circulating Exosomes as a Biomarker for Glioma.Semantic proximity Read

Characterization of systemic immunosuppression by IDH mutant glioma small extracellular vesicles.Semantic proximity Read

EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3Semantic proximity Read

Exosomal hsa-miR199a-3p Promotes Proliferation and Migration in NeuroblastomaSemantic proximity Read

Molecular profiles and immunomodulatory activities of glioblastoma-derived exosomesSemantic proximity Read

Roles of Cancer Exosomes in Immunosuppression and Immune EvasionSemantic proximity Read

Exosomes and Extracellular Vesicles in Myeloid Neoplasia: The Multiple and Complex Roles Played by These “Magic Bullets”Semantic proximity Read

Long noncoding RNA LPP-AS2 promotes glioma tumorigenesis via miR-7-5p/EGFR/PI3K/AKT/c-MYC feedback loopSemantic proximity Read

Analysis and Validation of TMED3 correlates with poor prognosis and tumor immune infiltration of gliomaSemantic proximity Read