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Article

Targeting miR-9 in Glioma Stem Cell-Derived Extracellular Vesicles: A Novel Diagnostic and Therapeutic Biomarker

19 May 2022

Abstract excerpt

BACKGROUND: Glioblastoma (GBM) is a lethal brain tumor with no effective strategies in early diagnosis and treatment. This study was aimed to assess the miRNA expression profiles in EVs from CSF and tissue of glioblastoma patients to identify significantly upregulated miRNAs and investigate the underlying neoplastic mechanisms. METHODS: EVs were measured by TEM and NTA assays. Differentially regulated miRNAs were...

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PMID: 35598381
DOI: 10.1016/j.tranon.2022.101451

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