Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3

14 Jan 2022

Abstract excerpt

BACKGROUND: Gliomas are the most common malignant primary brain tumours with a highly immunosuppressive tumour microenvironment (TME) and poor prognosis. Circular RNAs (circRNA), a newly found type of endogenous noncoding RNA, characterized by high stability, abundance, conservation, have been shown to play an important role in the pathophysiological processes and TME remodelling of various tumours. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Circular RNAs in diseases
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35031058
DOI: 10.1186/s12943-021-01485-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3PMID 35031058Read ↗

Circular RNA - circCLIP2 is predominantly expressed in GSC niche and enhances glioblastoma aggressiveness via EMT and ECM signalingSemantic proximity Read ↗

Transcriptome-wide analysis of circRNA and RBP profiles and their molecular and clinical relevance for GBMSemantic proximity Read ↗

CircRNF10 triggers a positive feedback loop to facilitate progression of glioblastoma via redeploying the ferroptosis defense in GSCsSemantic proximity Read ↗

Identification of a Functional circRNA-miRNA-mRNA Network and Inhibitory Effect of Hsa_circ_0001681 on GliomasSemantic proximity Read ↗

Long Non-Coding RNAs in Diagnosis, Treatment, Prognosis, and Progression of Glioma: A State-of-the-Art ReviewSemantic proximity Read ↗

Differential Expression of Circular RNAs in Glioblastoma Multiforme and Its Correlation with PrognosisSemantic proximity Read ↗

circMELK promotes glioblastoma multiforme cell tumorigenesis through the miR-593/EphB2 axisSemantic proximity Read ↗

New insights into long noncoding RNAs and their roles in glioma.Semantic proximity Read ↗

IGF2BP3 binding circGNB1 promotes the malignant phenotype of GSCs via miR-515-5p/miR-582-3p mediated XPR1 expression changeSemantic proximity Read ↗

Circular RNA Sequencing Reveals Serum Exosome Circular RNA Panel for High-Grade Astrocytoma DiagnosisSemantic proximity Read ↗

CSRP2 is involved in immune regulation and drug sensitivity in glioma cells by the LEF1- AS1/miR-128-3p/CSRP2 axisSemantic proximity Read ↗

Long noncoding RNA LPP-AS2 promotes glioma tumorigenesis via miR-7-5p/EGFR/PI3K/AKT/c-MYC feedback loopSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.