Article

Predicting peptide aggregation with protein language model embeddings

2025-09-29

Abstract excerpt

Amyloid fibrils, a form of peptide aggregate, are associated with multiple diseases and hinder the development of therapeutics. The experimental characterization of aggregating peptides is resource-intensive and data are scarce, limiting the development of accurate models. We present a deep-learning model, PALM (Predicting Aggregation with Language Model embeddings), which uses transfer learning to predict aggrega...

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Identifiers and source

Literature Corpus work: 90eb7835-5f2e-54bd-9748-83e6f5653749
DOI: 10.1101/2025.09.26.678773

Open publication

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