Article

<i>In Silico</i> identification and modelling of FDA-approved drugs targeting T-type calcium channels

2024-09-29

Abstract excerpt

Studies have shown that inhibition of the Ca v 3.1 T-type calcium channel can prevent or suppress neurological diseases, such as epileptic seizures and diabetic neuropathy. In this study we aimed to use in silico simulations to identify a U.S. Food and Drug Administration (FDA)-approved drug that can bind to the Ca v 3.1 T-type calcium channel. We used the automated docking suite GOLD v5.5 with the genetic algo...

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Identifiers and source

Literature Corpus work: 90cfbfff-6f96-5e29-ba31-84039d8f64b9
DOI: 10.1101/2024.09.27.615366

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