Article

Selection pressure dominates the use of synonymous codons in genes linked to epilepsy

2022-08-08

Abstract excerpt

Bioinformatic approaches were utilized to investigate the pattern of codon usage in 109 epilepsy-related genes. The genes were found to be rich in G and C nucleotides, with GC usage 7% higher than AT. Preferred codon analysis confirmed the dominance of G and C at the wobble position of codons. CAG is the most frequently used codon. The ENc analysis, on the other hand, did not reveal any exceptional codon usage bia...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 90c8d8a5-e42a-50b0-a1d4-c24ec9deac4c
DOI: 10.21203/rs.3.rs-1601828/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Selection pressure dominates the use of synonymous codons in genes linked to epilepsyDOI 10.21203/rs.3.rs-1601828/v2Read

Codon Usage Pattern of Genes Involved in Central Nervous System.Semantic proximity Read

Understanding the nucleotide composition and patterns of codon usage in the expression of human oral cancer genes.Semantic proximity Read

Insights into genetic architecture and disease associations of genes associated with different human blood group systems using codon usage bias.Semantic proximity Read

Significance and roles of synonymous codon usage in the evolutionary process of Proteus.Semantic proximity Read

A Crosstalk on Codon Usage in Genes Associated with Leukemia.Semantic proximity Read

Natural Selection Plays an Important Role in Shaping the Codon Usage of Structural Genes of the Viruses Belonging to the Coronaviridae Family.Semantic proximity Read

Codon usage pattern and its influencing factors in different genomes of hepadnaviruses.Semantic proximity Read

Synonymous codon usage and context analysis of genes associated with pancreatic cancer.Semantic proximity Read

Mapping the Inter- and Intra-genic Codon Usage Landscape in <i>Homo sapiens</i>Semantic proximity Read

The characteristic of codon usage pattern and its evolution of hepatitis C virus.Semantic proximity Read

Codon usage bias in prokaryotic genomes and environmental adaptationSemantic proximity Read

Codon Usage Optimization in the Prokaryotic Tree of Life: How Synonymous Codons Are Differentially Selected in Sequence Domains with Different Expression Levels and Degrees of Conservation.Semantic proximity Read