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Article

The characteristic of codon usage pattern and its evolution of hepatitis C virus.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2011

Hu Jin-song, Wang Qin-qin, Zhang Jie, Chen Hao-tai, Xu Zhi-wen, Zhu Ling, Ding Yao-zhong, Ma Li-na, Xu Kai, Gu Yuan-xing, Liu Yong-sheng

Abstract excerpt

To give a new perspective on the codon usage of the hepatitis C virus (HCV) and the factors accounting for shaping the codon usage pattern of the virus, the relative synonymous codon usage (RSCU) values, aromaticity and hydrophobicity of each polyprotein of the virus, effective number of codons (ENC) values and nucleotide contents were calculated to implement a comparative analysis to evaluate the dynamics of the...

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PMID: 21907310
DOI: 10.1016/j.meegid.2011.08.025

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