Article

Weighted 2D-kernel density estimations provide a new probabilistic measure for epigenetic age

2024-06-11

Abstract excerpt

<h4>Background</h4> Epigenetic aging signatures can provide insights into the human aging process. Within the last decade many alternative epigenetic clocks have been described, which are typically based on linear regression analysis of DNA methylation at multiple CG dinucleotides (CpGs). However, this approach assumes that the epigenetic modifications follow either a continuous linear or logarithmic trajectory....

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Literature Corpus work: 90b00626-e398-568f-abf9-0ecc9cf0ffba
DOI: 10.1101/2024.06.10.598169

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