Article

TOP2A is a potential biomarker and promotes platinum drug resistance in ovarian cancer: a bioinformatics and experimental analysis

2022-08-17

Abstract excerpt

<h4>Background: </h4> Ovarian cancer is a malignant tumour of the female genital system with a high lethality rate. Among which, serous ovarian cancer is the most prevalent type of ovarian cancer diagnosed. Many patients benefit from standard treatment, but some relapse due to chemotherapy resistance, resulting in increased mortality. TOP2A (topoisomerase DNA II alpha) as an oncogene has been reported to promote t...

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Literature Corpus work: 9028e111-e7c6-511d-b63c-21c2ff3a6d1a
DOI: 10.21203/rs.3.rs-1954513/v1

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