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TOP2A Serves as a Prognostic Marker Associated with Immune Infiltration in Hepatocellular Carcinoma

2022-06-07

Abstract excerpt

<h4>Background: </h4> TOP2A is a key enzyme that controls the topological state of DNA during DNA replication and transcription. We aim to explore the role of TOP2A in hepatocellular carcinoma (HCC). Methods The expression and prognostic value of TOP2A in HCC were analyzed by TIMER, TCGA, GEO, HPA, GEPIA and Kaplan-Meier plotter databases. The potential molecular mechanism of TOP2A in HCC was researched by GSEA s...

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Literature Corpus work
45d48f9e-2b1e-55a8-93f4-5977af591cde
DOI
10.21203/rs.3.rs-1690716/v1
Open publication

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