Article

PanGene-O-Meter: Intra-Species Diversity Based on Gene-Content

2025-09-01

Abstract excerpt

<h4>Background</h4> Bacterial genome evolution is shaped extensively by horizontal gene transfer, generating gene presence-absence variation that represents a major axis of functional diversity yet is largely invisible to core-genome-based similarity metrics. While genome-wide average nucleotide identity (ANI) remains the most widely used measure of similarity, it considers only the alignable fraction of compared...

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Literature Corpus work: 8fd8576b-6b1a-534c-a238-caf1df6623d7
DOI: 10.1101/2025.09.01.673544

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