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Benchmarking pangenome dynamics and horizontal gene transfer in Mycobacterium marinum evolution

17 Jun 2025

Abstract excerpt

Horizontal gene transfer (HGT) is a key driver of microbial evolution, promoting genetic diversity and contributing to the emergence of antibiotic resistance. This study explores the pangenome dynamics and HGT in Mycobacterium marinum (M. marinum), a close relative of Mycobacterium tuberculosis. Multiple pangenome datasets were analyzed to quantify gene gain, loss, and pangenome openness, utilizing Panstripe and...

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PMID: 40600140
DOI: 10.3389/fmicb.2025.1537826

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