Article

Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis

2024-11-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Collagen type X (ColXα1, encoded by COL10A1 ) is expressed specifically in the cartilage-to-bone transition, in bone marrow cells, and in osteoarthritic (OA) cartilage. We have previously shown that ColXα1 is expressed in breast tumor stroma, correlates with tumor-infiltrating lymphocytes, and predicts poor adjuvant therapy outcomes in ER + /HER2 + breast cancer. However,...

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Literature Corpus work: 8fa35aa8-7494-561c-8e8a-daf66d546334
DOI: 10.1101/2024.11.13.621984

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