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Clinical value and potential mechanisms of COL8A1 upregulation in breast cancer: a comprehensive analysis

14 Aug 2020

Abstract excerpt

BACKGROUND: The situation faced by breast cancer patients, especially those with triple-negative breast cancer, is still grave. More effective therapeutic targets are needed to optimize the clinical management of breast cancer. Although collagen type VIII alpha 1 chain (COL8A1) has been shown to be downregulated in BRIP1-knockdown breast cancer cells, its clinical role in breast cancer remains unknown. METHODS:...

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PMID: 32818022
DOI: 10.1186/s12935-020-01465-8

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