Article

Tumor Collagens Predict Genetic Features and Patient Outcomes

2022-11-10

Abstract excerpt

The extracellular matrix (ECM) is a critical determinant of tumor fate that reflects the output from myriad cell types in the tumor. The impact of ECM composition on patient outcomes remains largely unknown. Collagens constitute the principal substrate of the tumor ECM and yet have been largely overlooked as simple structural proteins. When RNA transcription from solid tumors in The Cancer Genome Atlas (TCGA) was...

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Literature Corpus work: 0ce708e3-57cb-5a8d-917b-779c80f7ddd7
DOI: 10.21203/rs.3.rs-2159960/v1

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