Article

Targeting hepatitis B vaccine escape using immunogenetics in Bangladeshi infants

2023-06-29

Abstract excerpt

Hepatitis B virus (HBV) vaccine escape mutants (VEM) are increasingly described, threatening progress in control of this virus worldwide. Here we studied the relationship between host genetic variation, vaccine immunogenicity and viral sequences implicating VEM emergence. In a cohort of 1,096 Bangladeshi children, we identified human leukocyte antigen (HLA) variants associated with response vaccine antigens. Using...

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Literature Corpus work: 8f709cc8-e663-572c-99ad-f9a413c5e4eb
DOI: 10.1101/2023.06.26.23291885

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