Article
Quasispecies characters of hepatitis B virus in immunoprophylaxis failure infants.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Jun 2018
Wang Xin, Deng Wanyan, Qian Keli, Deng Haijun, Huang Yong, Tu Zeng, Huang Ailong, Long Quanxin
Abstract excerpt
Hepatitis B vaccination prevents 80-95% of transmission and reduces the incidence of HBV in children. The variations in the a determinant of HBV surface antigen (HBsAg) have been reported to be the most prevalent cause for vaccine or antibody escape. There is a conflicting evidence on as to whether escape mutants arise de novo in infected infants or whether the mutants, that have preexisted maternally,...
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