Article

3D genomic capture of regulatory immuno-genetic profiles in COVID-19 patients for prognosis of severe COVID disease outcome

2021-03-16

Abstract excerpt

Human infection with the SARS-CoV-2 virus leads to coronavirus disease (COVID-19). A striking characteristic of COVID-19 infection in humans is the highly variable host response and the diverse clinical outcomes, ranging from clinically asymptomatic to severe immune reactions leading to hospitalization and death. Here we used a 3D genomic approach to analyse blood samples at the time of COVID diagnosis, from a glo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e48ce026-133c-5a27-9be2-6a91736153a1
DOI: 10.1101/2021.03.14.435295

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

3D genomic capture of regulatory immuno-genetic profiles in COVID-19 patients for prognosis of severe COVID disease outcomeDOI 10.1101/2021.03.14.435295Read

Development and validation of blood-based prognostic biomarkers for severity of COVID disease outcome using EpiSwitch 3D genomic regulatory immuno-genetic profilingSemantic proximity Read

Systems-level profiling of early peripheral host-response landscape variations across COVID-19 severity states in an Indian cohort.Semantic proximity Read

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection TrajectoriesSemantic proximity Read

COVID-19 severity is associated with immunopathology and multi-organ damageSemantic proximity Read

Characterisation of the blood RNA host response underpinning severity in COVID-19 patientsSemantic proximity Read

Identification of potentional immunological biomarkers of COVID-19 by blood transcriptome analysisSemantic proximity Read

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection TrajectoriesSemantic proximity Read

Single-cell multi-omics analysis of the immune response in COVID-19Semantic proximity Read

Identification of PBMC-based molecular signature associational with COVID-19 disease severitySemantic proximity Read

Temporal multi-omic analysis of COVID-19 in end-stage kidney diseaseSemantic proximity Read

A blood-based comprehensive and systems-level analysis of disease stages, immune regulation and symptoms in COVID-19 patientsSemantic proximity Read

CD177, a specific marker of neutrophil activation, is a hallmark of COVID-19 severity and deathSemantic proximity Read