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The cellular immune response to COVID-19 deciphered by single cell multi-omics across three UK centres

2021-01-15

Abstract excerpt

The COVID-19 pandemic, caused by SARS coronavirus 2 (SARS-CoV-2), has resulted in excess morbidity and mortality as well as economic decline. To characterise the systemic host immune response to SARS-CoV-2, we performed single-cell RNA-sequencing coupled with analysis of cell surface proteins, providing molecular profiling of over 800,000 peripheral blood mononuclear cells from a cohort of 130 patients with COVID-...

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Literature Corpus work
905d78e2-0b77-5354-ae4a-10a68c81a6e1
DOI
10.1101/2021.01.13.21249725
Open publication

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The cellular immune response to COVID-19 deciphered by single cell multi-omics across three UK centresDOI 10.1101/2021.01.13.21249725
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