Article

Divergent <i>in vivo</i> molecular responses to micro-fragmented adipose tissue and hyaluronic acid reveal disease-modifying activity of MFAT in inflammatory knee osteoarthritis

2026-06-22

Abstract excerpt

<h4>ABSTRACT</h4> Knee osteoarthritis (KOA) affects an estimated 374 million people worldwide and has no approved disease-modifying treatment. Intra-articular micro-fragmented adipose tissue (MFAT) outperformed hyaluronic acid (HA) on patient-reported outcomes in our recent double-blind randomized trial ( ISRCTN88966184 ). Yet, the molecular basis of this differential efficacy is unknown, and the two interventio...

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Literature Corpus work: 8ef095cb-a46a-5ed5-9035-030b42f191ed
DOI: 10.64898/2026.06.12.26355510

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