Article

Cell and Transcriptomic Diversity of Infrapatellar Fat Pad during Knee Osteoarthritis

2024-04-07

Abstract excerpt

<h4>Objectives</h4> In this study, we employ a multi-omic approach to identify major cell types and subsets, and their transcriptomic profiles within the infrapatellar fat pad (IFP), and to determine differences in the IFP based on knee osteoarthritis (KOA), sex, and obesity status. <h4>Methods</h4> Single-nucleus RNA sequencing of 82,924 nuclei from 21 IFPs (n=6 healthy control and n=15 KOA donors), spatial tra...

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Literature Corpus work: e4ab82b7-0878-570b-9bdf-e691ac475ceb
DOI: 10.1101/2024.04.04.588106

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