Article

Ki-67 labeling index and HIF-1α expression delineate prognostic heterogeneity within FNCLCC grade 2 soft-tissue sarcoma: a multicenter cohort study

2026-08-31

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> FNCLCC grade 2 (G2) soft-tissue sarcoma encompasses heterogeneous clinical outcomes. We evaluated whether the Ki-67 labeling index (LI) and hypoxia-inducible factor 1α (HIF-1α) expression could provide reproducible prognostic refinement within morphologically defined G2 disease. <bold>Methods:</bold> This retrospective five-center cohort included 320 adults...

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Literature Corpus work: 8e74c98e-80f0-587c-ad84-c1607a09f69f
DOI: 10.21203/rs.3.rs-10624787/v1

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