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MOSAIC: A Multi-Feature Genomic Instability Score Independently Predicts Sarcoma Survival in 2138 Patients.

American journal of clinical oncology - 1 Sept 2025

Schneider Daniel, Gluski Jacob, Brown Ethan D L, Mishra Akash, Sciubba Daniel M, Lo Sheng-Fu L

Abstract excerpt

OBJECTIVES: While genomic profiling has identified prognostic markers in sarcoma, clinical risk stratification remains largely histology-based. The combined impact of multiple genomic instability features on survival remains poorly understood. This study evaluated the prognostic utility of a novel Measure Of Sarcoma Aggregate Instability Complex (MOSAIC) Score. METHODS: We conducted a secondary analysis of 2138...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40323082
DOI: 10.1097/COC.0000000000001207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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