Article
The adaptive potential during nasopharyngeal colonisation of Streptococcus pneumoniae.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2011
Leung Marcus H Y, Oriyo Ndekya M, Gillespie Stephen H, Charalambous Bambos M
Abstract excerpt
Adaptation to host defences and antimicrobials is critical for Streptococcus pneumoniae (the pneumococcus) during colonisation of the nasopharynx--its only ecological habitat. The pneumococcus is highly transformable with the genome between different strains varying widely in both gene content and gene sequence. Thus, mixed strains colonising together will expand the genetic reservoir--"supragenome" for this...
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