Article

Sex Dependent Effects of Amyloid Precursor-Like Protein 2 in The SOD1-G37R Transgenic Mouse Model of MND.

2021-03-30

Abstract excerpt

<title>Abstract</title> <p>Introduction: Motor neurone disease (MND) is a neurodegenerative disorder characterised by progressive destruction of motor neurons, muscle paralysis and death. The amyloid precursor protein (APP) is highly expressed in the central nervous system and has been shown to modulate disease outcomes in MND. APP is part of a gene family that includes the amyloid precursor-like protein 1 (APLP...

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Literature Corpus work: 8e4acf64-20f5-51d6-9cce-7856bfd12f75
DOI: 10.21203/rs.3.rs-343057/v1

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