Social Isolation Causes Cortical and Trabecular Bone Loss in Adult Male, but not Female, C57BL/6J Mice

Abstract excerpt

Social isolation is a potent form of psychosocial stress and is a growing public health concern, particularly among older adults. Even prior to the onset of the COVID-19 pandemic, which has significantly increased the prevalence of isolation and loneliness, researchers have been concerned about a rising “epidemic” of loneliness. Isolation is associated with an increased risk for many physical and mental health dis...

Topics

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• Bone and Bones
• Disease Models, Animal
• Mice
• Mice, Inbred C57BL
• Phenotype
• Stress Disorders, Post-Traumatic
• Stress Responses and Cortisol
• Vitamin D Research Studies

Identifiers and source

Literature Corpus work

8e19a5fe-4b4e-5947-9e6d-fa81f68546f9

DOI

10.1101/2023.01.27.525939