Article
Genetic and phenotypic associations of social isolation and loneliness with sarcopenia.
Biodemography and social biology - 1 Jan 2026
Xu Xin, Zhang Haobin, Jing Fengshi, Guo Yawei, Chang Qingsong, Gao Tianyu, Xu Zhongzhi
Abstract excerpt
Social isolation and loneliness are recognized risk factors for adverse aging outcomes, but their effects on sarcopenia remain understudied. This study investigated the independent and combined effects of social isolation and loneliness on the risk of incident sarcopenia in two large prospective cohorts: CHARLS (n = 8,856) and ELSA (n = 5,561), including participants aged 50 years and older free of sarcopenia at...
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