Diastolic and systolic heart failure: different stages or distinct phenotypes of the heart failure syndrome?

Abstract excerpt

It remains uncertain if diastolic heart failure (DHF) is a distinct HF phenotype or a precursor stage of systolic HF (SHF). The unimodal distribution of left ventricular ejection fraction (LVEF) in HF, depressed LV long-axis shortening in DHF, and progression to eccentric LV remodeling in hypertension favor DHF and SHF as successive stages. These arguments are countered by the bimodal distribution of LVEF after...

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• Global Health
• Morbidity
• Phenotype
• Stroke Volume
• Survival Rate
• Ventricular Function, Left