Article

Effect of controlled human Plasmodium falciparum infection on B cell subsets in individuals with different levels of malaria immunity

2025-04-19

Abstract excerpt

<title>Abstract</title> Continuous exposure to <italic>Plasmodium falciparum</italic> (Pf) has been associated with alterations in B cells. We investigated the effect of controlled human malaria infection (CHMI) on B cell phenotypes in individuals with different Pf immunity status: malaria-naïve, immunized with PfSPZ-CVac and semi-immune (lifelong-exposed) volunteers. Compared to naïve, semi-immune but not vac...

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Literature Corpus work: 8d65eae2-4096-552d-b22e-aa1c969c037a
DOI: 10.21203/rs.3.rs-6221433/v1

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