Article
Neutrophil microvesicles drive atherosclerosis by delivering <i>miR-155</i> to atheroprone endothelium
2018-05-11
Abstract excerpt
Neutrophils have been implicated in the pathogenesis of atherosclerosis, a lipid-driven disease of arteries, but they are seldom found in atherosclerotic plaques. To resolve this longstanding paradox, we investigated whether neutrophil-derived microvesicles may influence arterial pathophysiology. Clinical and pre-clinical studies revealed that levels of circulating neutrophil microvesicles were enhanced by exposur...
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Identifiers and source
- Literature Corpus work
- 8d049611-d9bf-5898-8623-3b439c1e04fe
- DOI
- 10.1101/319392