Article

Mice generated with induced pluripotent stem cells derived from mucosal-associated invariant T cells

2022-07-27

Abstract excerpt

The function of mucosal-associated invariant T (MAIT) cells, a burgeoning member of innate-like T cells abundant in humans and implicated in many diseases, remains obscure. To explore this, mice with a rearranged T cell receptor (TCR) α or β locus, specific for MAIT cells, were generated via induced pluripotent stem cells derived from MAIT cells and designated Vα19 and Vβ8 mice, respectively. Both mice expressed l...

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Literature Corpus work: 8cf55f45-6882-5eec-b699-1e7be578b1ed
DOI: 10.1101/2022.07.27.501791

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