Back to search

Article

Optimal balancing of clinical factors in large scale clinical RNA-Seq studies

2021-07-01

Abstract excerpt

<h4>ABSTRACT</h4> Omics technologies are ubiquitous in biomedical research. However, improper sample selection is an often-overlooked complication with large omics studies, resulting in confounding effects that can disrupt the internal validity of a study and lead to false conclusions. Here, we present a method called BalanceIT , which uses a genetic algorithm to identify an optimal set of samples with balanced...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8cc92776-231c-5eed-b208-e770537480cb
DOI
10.1101/2021.06.30.450639
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Optimal balancing of clinical factors in large scale clinical RNA-Seq studiesDOI 10.1101/2021.06.30.450639
Select a neighboring publication to make it the new centre.