Article
Interpretable phenotype decoding from multicondition sequencing data with ALPINE.
Genome research - 3 Dec 2025
Lee Wei-Hao, Li Lechuan, Dannenfelser Ruth, Yao Vicky
Abstract excerpt
As sequencing techniques advance in precision, affordability, and diversity, an abundance of heterogeneous sequencing data has become available, encompassing a wide range of phenotypic features and biological perturbations. Unfortunately, increased resolution comes with the cost of increased complexity of the biological search space, even at the individual study level, as perturbations are now often examined...
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