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Calibration-free compression brings Evo 2 to its full million-token context on a single GPU

2026-08-28

Abstract excerpt

Evo 2 is the largest openly available genomic foundation model, but its forty billion parameter configuration cannot be loaded onto a single 80 GB accelerator, placing genome-scale analysis beyond most laboratories. We present TurboQuant-Bio, an open toolkit that compresses Evo 2's weights and attention cache to four bits without calibration data, and serves both through fused kernels. Compression is near-lossless...

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Literature Corpus work
8c79567a-04b3-5e0f-9913-d1de3a080869
DOI
10.64898/2026.08.28.747902
Open publication

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