Article

AI-Driven Analysis Unveils Functional Dynamics of Müller Cells in Retinal Autoimmune Inflammation

2025-03-06

Abstract excerpt

Müller cells are the most abundant glial cell type in the human and mouse retina, playing a crucial role in maintaining retinal homeostasis. However, many aspects of Müller cell function remain poorly characterized. In this study, we reanalyzed a single-cell RNA-seq (scRNA-seq) dataset from Aire-/- mice, focusing on Müller cells and T cells. We identified nine distinct Müller cell subgroups and five T cell subgrou...

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Literature Corpus work: 8c43b763-4272-57e4-b972-f7da6aa4bba7
DOI: 10.1101/2025.02.28.640907

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